FORMULATION AND EVALUATION OF TRANSDERMAL PATCH OF INDOMETHACIN CONTAINING PATCHOULI OIL AS NATURAL PENETRATION ENHANCER
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Naproxen Gel Containing Tulsi Oil as Penetration Enhancer
The present research has been undertaken with the aim to develop a transdermal gel formulation of naproxen, which would attenuate the gastrointestinal related toxicities associated with oral administration. The potential gastrointestinal disorders associated with oral administration of naproxen (NSAID’s) can be avoided by delivering the drug to the inflammation site. Gel based formulations are ...
متن کاملFormulation and in vitro evaluation of clotrimazole gel containing almond oil and tween 80 as penetration enhancer for topical application.
Achieving a desirable percutaneous absorption of drug molecule is a major concern in formulating dermal and transdermal products. The use of penetration enhancers could provide a successful mean for this purpose. The aim of this study was to develop Clotrimazole gel and to evaluate the effect of almond oil and tween 80 (in different concentrations), on the permeation of drug through rabbit skin...
متن کاملFormulation and Evaluation of Transdermal Patch of Repaglinide
Repaglinide has the half life of 1 hour, and bioavailability in the body is 56% due to first-pass metabolism. The total daily dose of Repaglinide is 16 mg (e.g., 4 mg four times daily depending on meal patterns); hence, it required frequent dosing. Transdermal patch of Repaglinide was prepared to sustain the release and improve bioavailability of drug and patient compliance. Different formulati...
متن کاملFormulation and Evaluation of Galantamine Gel as Drug Reservoir in Transdermal Patch Delivery System
Galantamine hydrobromide is formulated in tablets and capsules prescribed through oral delivery for the treatment of Alzheimer's disease. However, oral delivery of drugs can cause severe side effects such as nausea, vomiting, and gastrointestinal disturbance. Transdermal delivery of galantamine hydrobromide could avoid these unwanted side effects. In this work, galantamine hydrobromide was form...
متن کاملNatural Terpenes as Penetration Enhancers for Transdermal Drug Delivery.
The greatest hindrance for transdermal drug delivery (TDD) is the barrier property of skin, especially the stratum corneum (SC). Various methodologies have been investigated and developed to enhance the penetration of drugs through the skin. Among them, the most popular approach is the application of penetration enhancers (PEs), including natural terpenes, a very safe and effective class of PEs...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2017
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2017.v10i11.20926